General Information:

Id: 4,309 (click here to show other Interactions for entry)
Diseases: Metabolic
Homo sapiens
BTO:0001581 embryonic stem cell line H1, H9
article
Reference: Zhou J et al.(2009) mTOR supports long-term self-renewal and suppresses mesoderm and endoderm activities of human embryonic stem cells Proc. Natl. Acad. Sci. U.S.A. 106: 7840-7845 [PMID: 19416884]

Interaction Information:

Comment In response to rapamycin treatment, H9 cells up-regulated gene expression of CCNG2 (which encodes Cyclin G2) and programmed cell death 4 (PDCD4), both of which inhibit cell proliferation.
Formal Description
Interaction-ID: 44194

gene/protein

CCNG2

decreases_activity of

process

cell population proliferation

in H9 cells