General Information:

Id: 425 (click here to show other Interactions for entry)
Diseases: Amyotrophic lateral sclerosis
Mus musculus
in vitro experiments done with bovine SOD1
article
Reference: Harraz MM et al.(2008) SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS model J. Clin. Invest. 118: 659-670 [PMID: 18219391]

Interaction Information:

Comment H2O2 disrupts SOD1-Rac1 interactions.
Formal Description
Interaction-ID: 1865

drug/chemical compound

H2O2

decreases_quantity of

complex/PPI

Rac1-Sod1 complex