General Information:

Id: 4,230 (click here to show other Interactions for entry)
Diseases: Bipolar disorder
Circadian rhythm
Major depressive disorder - [OMIM]
Mus musculus
article
Reference: Mukherjee S et al.(2010) Knockdown of Clock in the ventral tegmental area through RNA interference results in a mixed state of mania and depression-like behavior Biol. Psychiatry 68: 503-511 [PMID: 20591414]

Interaction Information:

Comment VTA knock-down of Clock also altered circadian period and amplitude, suggesting a role for Clock in the VTA (ventral tegmental area) in the regulation of circadian rhythms.
Formal Description
Interaction-ID: 43220

gene/protein

CLOCK

affects_activity of

in ventral tegmental area