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Field	Query

Alzheimer disease
Amyotrophic lateral sclerosis
Autism
Bipolar disorder
COXPD
Cancer
Cardiovascular diseases
Diabetes mellitus, type II
Epilepsy
Farber lipogranulomatosis
Inflammatory bowel disease
Lung disease
Major depressive disorder
Multiple sclerosis
Muscular atrophy
Neutropenia, severe congenital
Other
Parkinson disease
Post-traumatic stress disorder
Postpartum depression
Rare disease
Schizophrenia

	Field	Term

General Information:

Id:	4,214 (click here to show other Interactions for entry)
Diseases:	Circadian rhythm Sleep disorders
Organism:	Mus musculus
Publication type:	article
Reference:	Hamdan AM et al.(2012) Intestinal expression of mouse Abcg2/breast cancer resistance protein (BCRP) gene is under control of circadian clock-activating transcription factor-4 pathway J. Biol. Chem. 287 [PMID: 22396548]

Interaction Information:

Comment	ATF4 bound time-dependently to the cAMP response element within the exon 1B promoter region of the Abcg2 gene, thereby causing the oscillation of BCRP protein abundance and its efflux pump function.
Formal Description Interaction-ID: 43177	gene/protein ATF4 increases_activity of process circadian rhythm

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