General Information:
Id: | 4,213 (click here to show other Interactions for entry) |
Diseases: |
Circadian rhythm
Sleep disorders |
Homo sapiens | |
article | |
Reference: | Moller-Levet CS et al.(2013) Effects of insufficient sleep on circadian rhythmicity and expression amplitude of the human blood transcriptome Proc Natl Acad Sci U S A 110 [PMID: 23440187] |
Interaction Information:
Comment | Prevalent circadian genes were defined as those targeted by probes that showed a significant circadian oscillation in transcript levels. Assessment of individual expression profiles for a prevalent oscillatory component with a 24-h period in the control condition identified 1,855 circadian genes, which included PER1, PER2, PER3, NPAS2, CSNK1E, RORA, NR1D1 (REVERB-alpha), NR1D2 (REV-ERB-beta), and other genes associated with circadian rhythms, sleep, and metabolism. |
Formal Description Interaction-ID: 47025 |
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Comment | Prevalent circadian genes were defined as those targeted by probes that showed a significant circadian oscillation in transcript levels. Assessment of individual expression profiles for a prevalent oscillatory component with a 24-h period in the control condition identified 1,855 circadian genes, which included PER1, PER2, PER3, NPAS2, CSNK1E, RORA, NR1D1 (REVERB-alpha), NR1D2 (REV-ERB-beta), and other genes associated with circadian rhythms, sleep, and metabolism. |
Formal Description Interaction-ID: 47026 |
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Comment | Prevalent circadian genes were defined as those targeted by probes that showed a significant circadian oscillation in transcript levels. Assessment of individual expression profiles for a prevalent oscillatory component with a 24-h period in the control condition identified 1,855 circadian genes, which included PER1, PER2, PER3, NPAS2, CSNK1E, RORA, NR1D1 (REVERB-alpha), NR1D2 (REV-ERB-beta), and other genes associated with circadian rhythms, sleep, and metabolism. |
Formal Description Interaction-ID: 47027 |
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Comment | Prevalent circadian genes were defined as those targeted by probes that showed a significant circadian oscillation in transcript levels. Assessment of individual expression profiles for a prevalent oscillatory component with a 24-h period in the control condition identified 1,855 circadian genes, which included PER1, PER2, PER3, NPAS2, CSNK1E, RORA, NR1D1 (REVERB-alpha), NR1D2 (REV-ERB-beta), and other genes associated with circadian rhythms, sleep, and metabolism. |
Formal Description Interaction-ID: 47028 |
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Comment | Prevalent circadian genes were defined as those targeted by probes that showed a significant circadian oscillation in transcript levels. Assessment of individual expression profiles for a prevalent oscillatory component with a 24-h period in the control condition identified 1,855 circadian genes, which included PER1, PER2, PER3, NPAS2, CSNK1E, RORA, NR1D1 (REVERB-alpha), NR1D2 (REV-ERB-beta), and other genes associated with circadian rhythms, sleep, and metabolism. |
Formal Description Interaction-ID: 47029 |
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Comment | Prevalent circadian genes were defined as those targeted by probes that showed a significant circadian oscillation in transcript levels. Assessment of individual expression profiles for a prevalent oscillatory component with a 24-h period in the control condition identified 1,855 circadian genes, which included PER1, PER2, PER3, NPAS2, CSNK1E, RORA, NR1D1 (REVERB-alpha), NR1D2 (REV-ERB-beta), and other genes associated with circadian rhythms, sleep, and metabolism. |
Formal Description Interaction-ID: 47030 |
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Drugbank entries | Show/Hide entries for RORA |
Comment | Prevalent circadian genes were defined as those targeted by probes that showed a significant circadian oscillation in transcript levels. Assessment of individual expression profiles for a prevalent oscillatory component with a 24-h period in the control condition identified 1,855 circadian genes, which included PER1, PER2, PER3, NPAS2, CSNK1E, RORA, NR1D1 (REVERB-alpha), NR1D2 (REV-ERB-beta), and other genes associated with circadian rhythms, sleep, and metabolism. |
Formal Description Interaction-ID: 47031 |
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Comment | Prevalent circadian genes were defined as those targeted by probes that showed a significant circadian oscillation in transcript levels. Assessment of individual expression profiles for a prevalent oscillatory component with a 24-h period in the control condition identified 1,855 circadian genes, which included PER1, PER2, PER3, NPAS2, CSNK1E, RORA, NR1D1 (REVERB-alpha), NR1D2 (REV-ERB-beta), and other genes associated with circadian rhythms, sleep, and metabolism. |
Formal Description Interaction-ID: 47032 |
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