General Information:

Id: 4,109 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Homo sapiens
Reference: Grosfeld A et al.(2002) Hypoxia-inducible factor 1 transactivates the human leptin gene promoter J. Biol. Chem. 277 [PMID: 12215445]

Interaction Information:

Comment Leptin is a new hypoxia-inducible gene, which is stimulated in a placental cell line through HIF-1 interaction with a consensus HRE site located at -116 in the proximal promoter.
Formal Description
Interaction-ID: 42398

increases_expression of