General Information:

Id: 4,068 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Mus musculus
C57BL/6 mouse
BTO:0003037 HT-22 cell
Reference: Xie L et al.(2013) Methylene blue induces macroautophagy through 5 adenosine monophosphate-activated protein kinase pathway to protect neurons from serum deprivation Front Cell Neurosci 7: 56 [PMID: 23653592]

Interaction Information:

Comment Methylene blue induces macroautophagy via, at partially, AMPK signaling. Both AMPKalpha and AMPKbeta1/2 protein levels were increased in vitro.
Formal Description
Interaction-ID: 41919

drug/chemical compound

Methylene blue

increases_expression of



in vitro
Drugbank entries Show/Hide entries for PRKAB2