General Information:

Id: 4,068 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Mus musculus
C57BL/6 mouse
BTO:0003037 HT-22 cell
Reference: Xie L et al.(2013) Methylene blue induces macroautophagy through 5 adenosine monophosphate-activated protein kinase pathway to protect neurons from serum deprivation Front Cell Neurosci 7: 56 [PMID: 23653592]

Interaction Information:

Comment Methylene blue could protect HT22 hippocampal cell death induced by serum deprivation, companied by induction of macroautophagy. Macroautophagy was induced in the cortex and hippocampus of mouse brains treated with methylene blue.
Formal Description
Interaction-ID: 41904

drug/chemical compound

Methylene blue

increases_activity of



in the cortex and hippocampus