General Information:
Id: | 4,062 |
Diseases: |
Alzheimer disease
- [OMIM]
|
Homo sapiens | |
BTO:0000793 SH-SY5Y cell | |
article | |
Reference: | Lira-De Leon KI et al.(2013) Molecular mechanism of tau aggregation induced by anionic and cationic dyes J. Alzheimers Dis. 35: 319-334 [PMID: 23435411] |
Interaction Information:
Comment | Anionic dyes such as Congo Red, Thiazine Red, and Thioflavin S are able to induce tau fibrillization in SH-SY5Y cells incubated with each dye for seven days. |
Formal Description Interaction-ID: 41867 |
drug/chemical compound increases_quantity of phenotype |
Comment | Anionic dyes such as Congo Red, Thiazine Red, and Thioflavin S are able to induce tau fibrillization in SH-SY5Y cells incubated with each dye for seven days. |
Formal Description Interaction-ID: 41871 |
drug/chemical compound Thiazine red increases_quantity of phenotype |
Comment | Anionic dyes such as Congo Red, Thiazine Red, and Thioflavin S are able to induce tau fibrillization in SH-SY5Y cells incubated with each dye for seven days. |
Formal Description Interaction-ID: 41872 |
drug/chemical compound Thioflavin S increases_quantity of phenotype |
Comment | Anionic dyes such as Congo Red, Thiazine Red, and Thioflavin S are able to induce tau fibrillization in SH-SY5Y cells. These tau aggregates were not observed when the Methylene Blue dye was added to the cell culture. |
Formal Description Interaction-ID: 41875 |
|
Comment | Anionic dyes such as Congo Red, Thiazine Red, and Thioflavin S are able to induce tau fibrillization in SH-SY5Y cells. These tau aggregates were not observed when the Methylene Blue dye was added to the cell culture. |
Formal Description Interaction-ID: 41876 |
|
Comment | Anionic dyes such as Congo Red, Thiazine Red, and Thioflavin S are able to induce tau fibrillization in SH-SY5Y cells. These tau aggregates were not observed when the Methylene Blue dye was added to the cell culture. |
Formal Description Interaction-ID: 41877 |
|
Comment | Tau can interact with anionic dyes in SH-SY5Y cells. |
Formal Description Interaction-ID: 41888 |
|