General Information:

Id: 4,051 (click here to show other Interactions for entry)
Diseases: Ewing sarcoma - [OMIM]
Homo sapiens
article
Reference: Aryee DN et al.(2010) Hypoxia modulates EWS-FLI1 transcriptional signature and enhances the malignant properties of Ewings sarcoma cells in vitro Cancer Res. 70: 4015-4023 [PMID: 20442286]

Interaction Information:

Comment EWS-FLI1 protein expression, which characterizes Ewing sarcoma, is up-regulated by hypoxia in a HIF-1alpha-dependent manner.
Formal Description
Interaction-ID: 41800

increases_expression of

gene/protein

EWSR1