CIDeRGeneral Information:
| Id: | 4,049 (click here to show other Interactions for entry) |
| Diseases: |
Diabetes mellitus, type II
- [OMIM]
Insulin resistance |
| Homo sapiens | |
| article | |
| Reference: | Grarup N et al.(2008) Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged Danes Diabetes 57: 2534-2540 [PMID: 18567820] |
Interaction Information:
| Comment | The ADAMTS9 rs4607103 and NOTCH2 rs10923931 variants did not significantly associate with measures of oral glucose-stimulated insulin response, insulin sensitivity, or obesity in the Inter99 cohort. Similar results were found when including all 5,964 treatment-naive individuals from the Inter99 cohort. |
|
Formal Description Interaction-ID: 41857 |
NOT affects_activity of |
| Comment | The ADAMTS9 rs4607103 and NOTCH2 rs10923931 variants did not significantly associate with measures of oral glucose-stimulated insulin response, insulin sensitivity, or obesity in the Inter99 cohort. Similar results were found when including all 5,964 treatment-naive individuals from the Inter99 cohort. |
|
Formal Description Interaction-ID: 41860 |
NOT affects_activity of |