General Information:

Id: 3,992 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mammalia
article/cited
Reference: Connor SC et al.(2010) Integration of metabolomics and transcriptomics data to aid biomarker discovery in type 2 diabetes Mol Biosyst 5: 909-921 [PMID: 20567778]

Interaction Information:

Comment The thermodynamically irreversible reactions that are unique to liver (and kidney) gluconeogenesis (pyruvate carboxylase PC, phosphoenolpyruvate carboxykinase PCK1, fructose 1,6-bisphosphatase FBP1, and glucose 6-phosphatase G6PC) are all up-regulated in the liver of diabetic db/db mice. (cited information)
Formal Description
Interaction-ID: 40916

gene/protein

FBP1

affects_activity of

process

gluconeogenesis

in liver
Drugbank entries Show/Hide entries for FBP1