General Information:

Id: 392 (click here to show other Interactions for entry)
Diseases: Amyotrophic lateral sclerosis
Homo sapiens
BTO:0001279 spinal cord; BTO:0000312 motoneuron
article
Reference: Kiaei M et al.(2006) Thalidomide and lenalidomide extend survival in a transgenic mouse model of amyotrophic lateral sclerosis J. Neurosci. 26: 2467-2473 [PMID: 16510725]

Interaction Information:

Comment Intense TNF-alpha and FasL immunoreactivity occurred in the lumbar spinal cord sections from an ALS patient with a SOD1 mutation (I113T) as well as sporadic ALS patients, whereas control tissues showed very little or no TNF-alpha and FasL immunoreactivity.
Formal Description
Interaction-ID: 13501

disease

Amyotrophic lateral sclerosis

increases_quantity of

gene/protein

TNF

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