General Information:

Id: 391 (click here to show other Interactions for entry)
Diseases: Amyotrophic lateral sclerosis
Mus musculus
SOD1(G93A) transgenic mouse
BTO:0001279 spinal cord; BTO:0000312 motoneuron
article
Reference: Kiaei M et al.(2006) Thalidomide and lenalidomide extend survival in a transgenic mouse model of amyotrophic lateral sclerosis J. Neurosci. 26: 2467-2473 [PMID: 16510725]

Interaction Information:

Comment IL-1RA RNA was elevated in vehicle-treated G93A mice compared with wild type (N1020 controls) and significantly elevated further in both lenalidomide- and thalidomide-treated G93A mice.
Formal Description
Interaction-ID: 1691

gene/protein mutant

SOD1-p.G93A

increases_expression of

gene/protein

IL1RN

in spinal cord; at 110 days of age