General Information:

Id: 391 (click here to show other Interactions for entry)
Diseases: Amyotrophic lateral sclerosis
Mus musculus
SOD1(G93A) transgenic mouse
BTO:0001279 spinal cord; BTO:0000312 motoneuron
article
Reference: Kiaei M et al.(2006) Thalidomide and lenalidomide extend survival in a transgenic mouse model of amyotrophic lateral sclerosis J. Neurosci. 26: 2467-2473 [PMID: 16510725]

Interaction Information:

Comment FasL immunostaining was found in both neurons and astrocytes similar to TNF-alpha. The increase of FasL immunoreactivity in G93A SOD1 mice occurred as early as 60 days.
Formal Description
Interaction-ID: 1613

gene/protein mutant

SOD1-p.G93A

increases_quantity of

gene/protein

FASLG

in spinal cord motor neurons; as early as 60 days