General Information:

Id: 3,919 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Homo sapiens
article
Reference: Al-Azzam SI et al.(2013) Effect of statin therapy on vaspin levels in type 2 diabetic patients Clin Pharmacol 5: 33-38 [PMID: 23449848]

Interaction Information:

Comment There was no statistically significant difference in vaspin levels between the study and control groups at baseline. In addition, patient age, body mass index, duration of diabetes, gender, blood pressure, peripheral neuropathy, and family history of cardiovascular disease, thyroid disease, diabetes, diabetic foot ulcer, heart disease, nephropathy, erectile dysfunction, and dyslipidemia were not significantly different between the study and control groups. There were no significant differences in systolic and diastolic blood pressure, lipid profile, biochemistry, glucose levels, white cell count, and creatine kinase between the study and control groups at baseline. The mean vaspin level was significantly increased in the study group after treatment with simvastatin , but not in the control group.
Formal Description
Interaction-ID: 39779

drug/chemical compound

Simvastatin

increases_quantity of

gene/protein

SERPINA12

in blood serum; in type 2 diabetic patients
Drugbank entries Show/Hide entries for Simvastatin