General Information:

Id: 3,911
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Homo sapiens
female
article
Reference: Culver AL et al.(2012) Statin use and risk of diabetes mellitus in postmenopausal women in the Womens Health Initiative Arch. Intern. Med. 172: 144-152 [PMID: 22231607]

Interaction Information:

Comment The results of this study imply that statin use conveys an increased risk of new-onset DM in postmenopausal women. In keeping with the findings of other studies, the results suggest that statin-induced DM is a medication class effect and not related to potency or to individual statin. However, the data set contains unequal representation of statins that may have influenced the outcomes. In addition, women who took statins may have changed statin type prior to incident DM. Results may actually reflect a changing market and demand and include those statins that were not available at baseline.
Formal Description
Interaction-ID: 39686

drug/chemical compound

Statin

increases_activity of

in postmenopausal women