General Information:

Id: 3,892 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mammalia
article
Reference: Ringseis R et al.(2012) Regulation of Genes Involved in Carnitine Homeostasis by PPARalpha across Different Species (Rat, Mouse, Pig, Cattle, Chicken, and Human) PPAR Res 2012 [PMID: 23150726]

Interaction Information:

Comment It was shown that elevation of hepatic carnitine concentration in response to fasting, or fibrates occurs only in wild-type mice but not in transgenic mice lacking a functional PPARalpha protein strengthening the assumption that PPARalpha is a critical regulator of carnitine homeostasis.
Formal Description
Interaction-ID: 39378

gene/protein

PPARA

increases_quantity of

drug/chemical compound

Carnitine

in liver
Drugbank entries Show/Hide entries for PPARA