General Information:

Id: 3,892 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mammalia
article
Reference: Ringseis R et al.(2012) Regulation of Genes Involved in Carnitine Homeostasis by PPARalpha across Different Species (Rat, Mouse, Pig, Cattle, Chicken, and Human) PPAR Res 2012 [PMID: 23150726]

Interaction Information:

Comment Peroxisome proliferator-activated receptor alpha (PPARalpha) is considered a master transcriptional regulator of lipid metabolism and energy homeostasis, because typical genes regulated by PPARalpha are involved in all aspects of fatty acid catabolism (cellular fatty acid uptake, activation of fatty acids, intracellular fatty acid transport, import of fatty acids into the mitochondria, and mitochondrial and peroxisomal fatty acid beta-oxidation), ketogenesis, as well as gluconeogenesis.
Formal Description
Interaction-ID: 39372

gene/protein

PPARA

affects_activity of

process

gluconeogenesis

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