General Information:

Id: 3,875 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Homo sapiens
article
Reference: Rise P et al.(2001) Statins enhance arachidonic acid synthesis in hypercholesterolemic patients Nutr Metab Cardiovasc Dis 11: 88-94 [PMID: 11434193]

Interaction Information:

Comment The data show that an increase in arachidonic acid synthesis due to enhanced delta 5 desaturation is a major effect of statin treatment, and has the same order of magnitude as the reduction in plasma cholesterol levels.
Formal Description
Interaction-ID: 39052

drug/chemical compound

Statin

increases_activity of

process

arachidonic acid biosynthetic process