General Information:

Id: 385 (click here to show other Interactions for entry)
Diseases: Amyotrophic lateral sclerosis
Homo sapiens
BTO:0003350 BV-2 cell
article
Reference: Liu Y et al.(2009) Expression of amyotrophic lateral sclerosis-linked SOD1 mutant increases the neurotoxic potential of microglia via TLR2 J. Biol. Chem. 284: 3691-3699 [PMID: 19091752]

Interaction Information:

Comment P47-PHOX mediates SOD1 G93A mutation-enhanced oxidative stress and subsequent TNF-alpha secretion following TLR2 stimulation.
Formal Description
Interaction-ID: 1598

gene/protein

NCF1

affects_quantity of

gene/protein

TNF

in TLR2 stimulated murine microglial cell line BV-2; if SOD1(G93A) is overexpressed
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