General Information:

Id: 3,819 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mammalia
review
Reference: Aguilar D and Solomon SD(2006) ACE inhibitors and angiotensin receptor antagonists and the incidence of new-onset diabetes mellitus: an emerging theme Drugs 66: 1169-1177 [PMID: 16827595]

Interaction Information:

Comment Deleterious effects of angiotensin II on the insulin-signaling pathway through the phosphoinositol-3-kinase/protein kinase C signaling pathway in skeletal muscle and cardiovascular tissue also appear to be contributing to insulin resistance.
Formal Description
Interaction-ID: 38219

gene/protein

Angiotensin II

decreases_activity of

in skeletal muscle, in cardiac muscle