General Information:

Id: 3,792 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Reference: Srikanth V et al.(2011) Advanced glycation endproducts and their receptor RAGE in Alzheimers disease Neurobiol. Aging 32: 763-777 [PMID: 19464758]

Interaction Information:

Comment The AGE-induced increase in oxidized glutathione could be prevented by the radical scavengers N-acetylcysteine, alpha-lipoic acid and 17beta-estradiol or by application of catalase, indicating that superoxide and hydrogen peroxide production precedes the AGE-mediated depletion of reduced glutathione.
Formal Description
Interaction-ID: 37649

drug/chemical compound

Advanced glycation end-product

increases_quantity of

drug/chemical compound

Glutathione disulfide