General Information:

Id: 3,792 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Mammalia
review
Reference: Srikanth V et al.(2011) Advanced glycation endproducts and their receptor RAGE in Alzheimers disease Neurobiol. Aging 32: 763-777 [PMID: 19464758]

Interaction Information:

Comment Formation of covalently crosslinked high molecular weight Abeta oligomers is accelerated by micromolar amounts of copper (Cu+, Cu2+) and iron (Fe2+, Fe3+) ions.
Formal Description
Interaction-ID: 37642

drug/chemical compound

Fe2+

increases_quantity of

complex/PPI

Amyloid beta peptide (oligomer)

The formation of covalently crosslinked high molecular weight Abeta oligomers is accelerated