General Information:

Id: 3,784 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Mammalia
article
Reference: Murata N et al.(2010) Silymarin attenuated the amyloid beta plaque burden and improved behavioral abnormalities in an Alzheimers disease mouse model Biosci. Biotechnol. Biochem. 74: 2299-2306 [PMID: 21071836]

Interaction Information:

Comment A marked suppression of Abeta fibril formation and neurotoxicity in PC12 cells after silymarin (an extract of milk thistle) treatment in vitro was observed.
Formal Description
Interaction-ID: 80181

drug/chemical compound

Silibinin

decreases_activity of

in PC12 cells