General Information:

Id: 3,784 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Mammalia
article
Reference: Murata N et al.(2010) Silymarin attenuated the amyloid beta plaque burden and improved behavioral abnormalities in an Alzheimers disease mouse model Biosci. Biotechnol. Biochem. 74: 2299-2306 [PMID: 21071836]

Interaction Information:

Comment Some studies showed a significant reduction in brain Abeta deposition and improvement in behavioral abnormalities in APP transgenic mice that had been preventively treated with a powdered diet containing 0.1% silymarin for 6 months.
Formal Description
Interaction-ID: 37361

drug/chemical compound

Silibinin

decreases_quantity of

in brain; of APP transgenic mice