General Information:

Id: 377 (click here to show other Interactions for entry)
Diseases: Amyotrophic lateral sclerosis
Mus musculus
SOD1(G93A) transgenic mouse
BTO:0001279 spinal cord
article
Reference: Tortarolo M et al.(2003) Persistent activation of p38 mitogen-activated protein kinase in a mouse model of familial amyotrophic lateral sclerosis correlates with disease progression Mol. Cell. Neurosci. 23: 180-192 [PMID: 12812752]

Interaction Information:

Comment In SOD1G93A mice with advanced disease (19 weeks), p38MAPK-P fluorescence was increased in the whole gray matter of the spinal cord including the substantia gelatinosa.
Formal Description
Interaction-ID: 1536

gene/protein mutant

SOD1-p.G93A

increases_activity of

gene/protein

p38 MAPK

in spinal cord