General Information:

Id: 3,686 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Rattus norvegicus
Reference: Liu Y et al.(2012) Fetal rat metabonome alteration by prenatal caffeine ingestion probably due to the increased circulatory glucocorticoid level and altered peripheral glucose and lipid metabolic pathways Toxicol. Appl. Pharmacol. 262: 205-216 [PMID: 22583948]

Interaction Information:

Comment Prenatal caffeine ingestion characteristically changes the fetal metabonome, which is probably attributed to the alterations of glucose and lipid metabolic pathways induced by increased circulatory glucocorticoid (GC), activated GC metabolism and enhanced glucocorticoid receptor (GR) expression in peripheral metabolic tissues.
Formal Description
Interaction-ID: 35493