General Information:

Id: 3,662 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Homo sapiens
article
Reference: Owen JB et al.(2009) Proteomics-determined differences in the concanavalin-A-fractionated proteome of hippocampus and inferior parietal lobule in subjects with Alzheimers disease and mild cognitive impairment: implications for progression of AD J. Proteome Res. 8: 471-482 [PMID: 19072283]

Interaction Information:

Comment Con-A-associated brain proteins in MCI: DRP2, GRP-78, SDS22, GFAP, SNCB.
Formal Description
Interaction-ID: 35055

drug/chemical compound

Concanavalin-A

interacts (colocalizes) with

gene/protein

DRP2

in MCI
Comment Con-A-associated brain proteins in AD: GDH/GLUD1, GFAP, HSP90, TPM3, XAP4, ENO1, ENO2.
Formal Description
Interaction-ID: 35056

drug/chemical compound

Concanavalin-A

interacts (colocalizes) with

gene/protein

GLUD1

in AD
Drugbank entries Show/Hide entries for GLUD1
Comment Con-A-associated brain proteins in MCI: DRP2, GRP-78/HSPA5, SDS22, GFAP, SNCB.
Formal Description
Interaction-ID: 35063

drug/chemical compound

Concanavalin-A

interacts (colocalizes) with

gene/protein

HSPA5

in MCI
Drugbank entries Show/Hide entries for HSPA5
Comment Con-A-associated brain proteins in MCI: DRP2, GRP-78, SDS22/PPP1R7, GFAP, SNCB.
Formal Description
Interaction-ID: 35064

drug/chemical compound

Concanavalin-A

interacts (colocalizes) with

gene/protein

PPP1R7

in MCI
Comment Con-A-associated brain proteins in MCI: DRP2, GRP-78, SDS22, GFAP, SNCB.
Formal Description
Interaction-ID: 35065

drug/chemical compound

Concanavalin-A

interacts (colocalizes) with

gene/protein

GFAP

in MCI
Comment Con-A-associated brain proteins in MCI: DRP2, GRP-78, SDS22, GFAP, SNCB.
Formal Description
Interaction-ID: 35066

drug/chemical compound

Concanavalin-A

interacts (colocalizes) with

gene/protein

SNCB

in MCI
Comment Con-A-associated brain proteins in AD: GDH, GFAP, HSP90, TPM3, XAP4, ENO1, ENO2.
Formal Description
Interaction-ID: 35067

drug/chemical compound

Concanavalin-A

interacts (colocalizes) with

gene/protein

GFAP

in AD
Comment Con-A-associated brain proteins in AD: GDH, GFAP, HSP90, TPM3, XAP4, ENO1, ENO2.
Formal Description
Interaction-ID: 35068

drug/chemical compound

Concanavalin-A

interacts (colocalizes) with

gene/protein

HSP90AA1

in AD
Drugbank entries Show/Hide entries for HSP90AA1
Comment Con-A-associated brain proteins in AD: GDH, GFAP, HSP90, TPM3, XAP4, ENO1, ENO2.
Formal Description
Interaction-ID: 35069

drug/chemical compound

Concanavalin-A

interacts (colocalizes) with

gene/protein

TPM3

in AD
Comment Con-A-associated brain proteins in AD: GDH, GFAP, HSP90, TPM3, XAP4/POLR2E, ENO1, ENO2.
Formal Description
Interaction-ID: 35070

drug/chemical compound

Concanavalin-A

interacts (colocalizes) with

gene/protein

POLR2E

in AD
Comment Con-A-associated brain proteins in AD: GDH, GFAP, HSP90, TPM3, XAP4, ENO1, ENO2.
Formal Description
Interaction-ID: 35071

drug/chemical compound

Concanavalin-A

interacts (colocalizes) with

gene/protein

ENO1

in AD
Comment Con-A-associated brain proteins in AD: GDH, GFAP, HSP90, TPM3, XAP4, ENO1, ENO2.
Formal Description
Interaction-ID: 35072

drug/chemical compound

Concanavalin-A

interacts (colocalizes) with

gene/protein

ENO2

in AD
Drugbank entries Show/Hide entries for ENO2
Comment Concanavalin-A (Con-A) binds to N-linked glycoproteins, but hydrophobic sites on non-glycoproteins are also known to bind Con-A.
Formal Description
Interaction-ID: 35099

drug/chemical compound

Concanavalin-A

interacts (colocalizes) with

drug/chemical compound

N-linked glycoprotein

Comment Concanavalin-A (Con-A) binds to N-linked glycoproteins, but hydrophobic sites on non-glycoproteins are also known to bind Con-A.
Formal Description
Interaction-ID: 35100

drug/chemical compound

Concanavalin-A

interacts (colocalizes) with

drug/chemical compound

Non-glycoprotein (hydrophobic sites)