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Field	Query

Alzheimer disease
Amyotrophic lateral sclerosis
Autism
Bipolar disorder
COXPD
Cancer
Cardiovascular diseases
Diabetes mellitus, type II
Epilepsy
Farber lipogranulomatosis
Inflammatory bowel disease
Lung disease
Major depressive disorder
Multiple sclerosis
Muscular atrophy
Neutropenia, severe congenital
Other
Parkinson disease
Post-traumatic stress disorder
Postpartum depression
Rare disease
Schizophrenia

	Field	Term

General Information:

Id:	3,659 (click here to show other Interactions for entry)
Diseases:	Diabetes mellitus, type II - [OMIM] Insulin resistance
Organism:	Mammalia
Publication type:	review
Reference:	Prentki M and Madiraju SR(2012) Glycerolipid/free fatty acid cycle and islet beta-cell function in health, obesity and diabetes Mol. Cell. Endocrinol. 353: 88-100 [PMID: 22108437]

Interaction Information:

Comment	Phospholipase-D-generated phosphatidic acid (PA) is important in GSIS at the exocytotic step, but it is uncertain whether PA derived from lipogenesis is implicated in this process.
Formal Description Interaction-ID: 34996	drug/chemical compound Phosphatidate affects_activity of process insulin secretion involved in cellular response to glucose stimulus if PA is phospholipase-D-generated

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