General Information:

Id: 3,659 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mammalia
review
Reference: Prentki M and Madiraju SR(2012) Glycerolipid/free fatty acid cycle and islet beta-cell function in health, obesity and diabetes Mol. Cell. Endocrinol. 353: 88-100 [PMID: 22108437]

Interaction Information:

Comment The importance of long-chain acylcoenzyme A synthase activity in insulin secretion became evident as long-chain acyl-coenzyme A synthase inhibitor, triacsin-C, strongly obliterated the FFA-augmented glucose-stimulated insulin secretion (GSIS) in rat islets.
Formal Description
Interaction-ID: 34896

gene/protein

ACSL

affects_activity of

in pancreas, in pancreatic beta cells