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Field	Query

Alzheimer disease
Amyotrophic lateral sclerosis
Autism
Bipolar disorder
COXPD
Cancer
Cardiovascular diseases
Diabetes mellitus, type II
Epilepsy
Farber lipogranulomatosis
Inflammatory bowel disease
Lung disease
Major depressive disorder
Multiple sclerosis
Muscular atrophy
Neutropenia, severe congenital
Other
Parkinson disease
Post-traumatic stress disorder
Postpartum depression
Rare disease
Schizophrenia

	Field	Term

General Information:

Id:	3,659 (click here to show other Interactions for entry)
Diseases:	Diabetes mellitus, type II - [OMIM] Insulin resistance
Organism:	Mammalia
Publication type:	review
Reference:	Prentki M and Madiraju SR(2012) Glycerolipid/free fatty acid cycle and islet beta-cell function in health, obesity and diabetes Mol. Cell. Endocrinol. 353: 88-100 [PMID: 22108437]

Interaction Information:

Comment	The importance of long-chain acylcoenzyme A synthase activity in insulin secretion became evident as long-chain acyl-coenzyme A synthase inhibitor, triacsin-C, strongly obliterated the FFA-augmented glucose-stimulated insulin secretion (GSIS) in rat islets.
Formal Description Interaction-ID: 34896	gene/protein ACSL affects_activity of process insulin secretion involved in cellular response to glucose stimulus in pancreas, in pancreatic beta cells

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