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Field	Query

Alzheimer disease
Amyotrophic lateral sclerosis
Autism
Bipolar disorder
COXPD
Cancer
Cardiovascular diseases
Diabetes mellitus, type II
Epilepsy
Farber lipogranulomatosis
Inflammatory bowel disease
Lung disease
Major depressive disorder
Multiple sclerosis
Muscular atrophy
Neutropenia, severe congenital
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Postpartum depression
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	Field	Term

General Information:

Id:	3,656 (click here to show other Interactions for entry)
Diseases:	Diabetes mellitus, type II - [OMIM] Insulin resistance
Organism:	Mammalia
Publication type:	review
Reference:	Newsholme P et al.(2007) Amino acid metabolism, insulin secretion and diabetes Biochem. Soc. Trans. 35: 1180-1186 [PMID: 17956307]

Interaction Information:

Comment	Beta-cells overexpressing L-glutamate decarboxylase showed a reduced glutamate content and a reduction in glucose-stimulated insulin secretion.
Formal Description Interaction-ID: 34847	gene/protein GAD2 affects_activity of process insulin secretion involved in cellular response to glucose stimulus in pancreas
Drugbank entries	Show/Hide entries for GAD2
Drugbank DB00114	Pyridoxal Phosphate cofactor GAD2
Drugbank DB00142	L-Glutamic Acid not specified GAD2
Drugbank DB00142	L-Glutamic Acid not specified GAD2

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