General Information:

Id: 3,632 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Fatty liver disease, nonalcoholic
Insulin resistance
Obesity - [OMIM]
Mammalia
review
Reference: Prawitt J et al.(2011) Bile acid metabolism and the pathogenesis of type 2 diabetes Curr Diab Rep 11: 160-166 [PMID: 21431855]

Interaction Information:

Comment FXR controls adipocyte differentiation and function by promoting peroxisome proliferator-activated receptor-gamma activity and inhibiting the Wnt/beta-catenin pathway.
Formal Description
Interaction-ID: 34487

gene/protein

NR1H4

decreases_activity of

Drugbank entries Show/Hide entries for NR1H4