General Information:

Id: 3,632 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Fatty liver disease, nonalcoholic
Insulin resistance
Obesity - [OMIM]
Mammalia
review
Reference: Prawitt J et al.(2011) Bile acid metabolism and the pathogenesis of type 2 diabetes Curr Diab Rep 11: 160-166 [PMID: 21431855]

Interaction Information:

Comment In addition to the key role of FXR in the control of insulin sensitivity, FXR expression has been reported to play a role in the pancreas, where it regulates glucose-induced insulin secretion and protects against lipotoxicity.
Formal Description
Interaction-ID: 34442
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