General Information:

Id: 3,619 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Metabolic syndrome
Rattus norvegicus
male
article
Reference: Liaset B et al.(2011) Nutritional regulation of bile acid metabolism is associated with improved pathological characteristics of the metabolic syndrome J. Biol. Chem. 286 [PMID: 21680746]

Interaction Information:

Comment In contrast to previous reports from bile acid-fed mice, the authors observed a down-regulation of liver Ppar-alpha in the SPH-treated rats. Concomitantly, liver acyl-CoA oxidase 1 (Acox1) expression was reduced, whereas carnitine palmitoyltransferase 1a (Cpt-1a) mRNA level was unaltered.
Formal Description
Interaction-ID: 34237

environment

high-fat diet, salmon protein hydrolysate-based

decreases_expression of

gene/protein

PPARA

in liver
Drugbank entries Show/Hide entries for PPARA