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Field	Query

Alzheimer disease
Amyotrophic lateral sclerosis
Autism
Bipolar disorder
COXPD
Cancer
Cardiovascular diseases
Diabetes mellitus, type II
Epilepsy
Farber lipogranulomatosis
Inflammatory bowel disease
Lung disease
Major depressive disorder
Multiple sclerosis
Muscular atrophy
Neutropenia, severe congenital
Other
Parkinson disease
Post-traumatic stress disorder
Postpartum depression
Rare disease
Schizophrenia

	Field	Term

General Information:

Id:	3,576 (click here to show other Interactions for entry)
Diseases:	Cholestasis, progressive familial intrahepatic 2 - [OMIM] Diabetes mellitus, type II - [OMIM] Insulin resistance
Organism:	Mammalia
Publication type:	review
Reference:	Li T and Chiang JY(2012) Bile Acid signaling in liver metabolism and diseases J Lipids 2012 [PMID: 21991404]

Interaction Information:

Comment	FXR is also expressed in pancreatic beta cells and positively regulates glucose-dependent insulin secretion.
Formal Description Interaction-ID: 33529	gene/protein NR1H4 increases_activity of process insulin secretion involved in cellular response to glucose stimulus
Drugbank entries	Show/Hide entries for NR1H4
Drugbank DB02545	Fexaramine not specified NR1H4
Drugbank DB06777	Chenodeoxycholic acid other NR1H4
Drugbank DB08220	(8alpha,10alpha,13alpha,17beta)-17-[(4-h ... not specified NR1H4
Drugbank DB02545	Fexaramine not specified NR1H4

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