General Information:

Id: 3,542
Diseases: Neurological
Homo sapiens
Reference: Wang GL et al.(1995) Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension Proc. Natl. Acad. Sci. U.S.A. 92: 5510-5514 [PMID: 7539918]

Interaction Information:

Comment HIF-1 alpha and HIF-1 beta (ARNT) RNA and protein levels were induced in cells exposed to 1% O2 and decayed rapidly upon return of the cells to 20% O2, consistent with the role of HIF-1 as a mediator of transcriptional responses to hypoxia.
Formal Description
Interaction-ID: 32951

increases_expression of



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