General Information:

Id: 352 (click here to show other Interactions for entry)
Diseases: Parkinson disease
Mus musculus
C57BL/6 mouse
article
Reference: Hartmann A et al.(2001) Caspase-8 is an effector in apoptotic death of dopaminergic neurons in Parkinsons disease, but pathway inhibition results in neuronal necrosis. J. Neurosci. 21: 2247-2255 [PMID: 11264300]

Interaction Information:

Comment Caspase 8 activation precedes and is not the consequence of cell death.
Formal Description
Interaction-ID: 1394

gene/protein

CASP8

increases_activity of

process

neuron death