General Information:

Id: 3,510
Diseases: Major depressive disorder - [OMIM]
Mammalia
review
Reference: Feng XH and Derynck R(2005) Specificity and versatility in tgf-beta signaling through Smads Annu. Rev. Cell Dev. Biol. 21: 659-693 [PMID: 16212511]

Interaction Information:

Comment Tob protein also binds inhibitory Smads and enhance their interactions with receptors, thereby inhibiting TGF-beta signal- ing at the receptor level (potentially associated with depression)
Formal Description
Interaction-ID: 32580

gene/protein

TOB1

decreases_activity of