General Information:

Id: 3,505 (click here to show other Interactions for entry)
Diseases: Neurological
Homo sapiens
BTO:0000567 Hela
Reference: Kuratomi G et al.(2005) NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptor Biochem. J. 386: 461-470 [PMID: 15496141]

Interaction Information:

Comment Decreased expression level of NEDD4-2 results in enhancement of TGF-beta and BMP signalling.
Formal Description
Interaction-ID: 32522



decreases_activity of