General Information:

Id: 3,503 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mus musculus
male
PPARalpha-/- mouse
article
Reference: Makowski L et al.(2009) Metabolic profiling of PPARalpha-/- mice reveals defects in carnitine and amino acid homeostasis that are partially reversed by oral carnitine supplementation FASEB J. 23: 586-604 [PMID: 18945875]

Interaction Information:

Comment In both the fed and fasted states, expression of the carnitine/organic cation transporter (OCTN2 or SLC22A5) was reduced by 40% in PPARalpha -/- compared to PPARalpha +/+ mice.
Formal Description
Interaction-ID: 32570

gene/protein

PPARA

affects_expression of

gene/protein

SLC22A5

Drugbank entries Show/Hide entries for PPARA or SLC22A5