General Information:

Id: 3,471 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Obesity - [OMIM]
Mammalia
review
Reference: Bain JR et al.(2009) Metabolomics applied to diabetes research: moving from information to knowledge Diabetes 58: 2429-2443 [PMID: 19875619]

Interaction Information:

Comment Targeted GC-MS and LC-MS-MS analysis has provided deeper insights by showing that PPAR-alpha knockout results in fasting hypoglycemia accompanied by depletion of TCA cycle intermediates and free carnitine and short-chain acylcarnitines, as well as accumulation of long-chain acyl CoAs in skeletal muscle.
Formal Description
Interaction-ID: 32397

gene/protein

PPARA

affects_quantity of

drug/chemical compound

Short-chain acylcarnitine

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