General Information:

Id: 346 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Fatty liver disease, nonalcoholic
Insulin resistance
Rattus norvegicus
BTO:0000759 liver
article
Reference: Zhou G et al.(2001) Role of AMP-activated protein kinase in mechanism of metformin action J. Clin. Invest. 108: 1167-1174 [PMID: 11602624]

Interaction Information:

Comment Both AICAR and metformin treatment stimulated fatty acid oxidation in isolated rat hepatocytes.
Formal Description
Interaction-ID: 1408

drug/chemical compound

AICAR

increases_activity of

in liver
Drugbank entries Show/Hide entries for AICAR