General Information:

Id: 33 (click here to show other Interactions for entry)
Diseases: Amyotrophic lateral sclerosis
Homo sapiens
BTO:0000661 JURKAT cell
article
Reference: Moretti S et al.(2008) Semaphorin3A signaling controls Fas (CD95)-mediated apoptosis by promoting Fas translocation into lipid rafts. Blood 111: 2290-2299 [PMID: 18056484]

Interaction Information:

Comment Sema3A increases Fas-mediated caspase activation in Jurkat (type II), but not in HUT-78 (type I), cells. Fas-mediated activation of Caspase-8 and Caspase-3 leads to apoptosis.
Formal Description
Interaction-ID: 81

gene/protein

FAS

increases_activity of

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