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Field	Query

Alzheimer disease
Amyotrophic lateral sclerosis
Autism
Bipolar disorder
COXPD
Cancer
Cardiovascular diseases
Diabetes mellitus, type II
Epilepsy
Farber lipogranulomatosis
Inflammatory bowel disease
Lung disease
Major depressive disorder
Multiple sclerosis
Muscular atrophy
Neutropenia, severe congenital
Other
Parkinson disease
Post-traumatic stress disorder
Postpartum depression
Rare disease
Schizophrenia

	Field	Term

General Information:

Id:	3,397 (click here to show other Interactions for entry)
Diseases:	Major depressive disorder - [OMIM] Neurological
Organism:	Homo sapiens
Tissue/Cell line:	BTO:0002181 HEK-293T cell
Publication type:	article
Reference:	Lin X et al.(2006) PPM1A functions as a Smad phosphatase to terminate TGFbeta signaling Cell 125: 915-928 [PMID: 16751101]

Interaction Information:

Comment	PPM1A dephosphorylates SMAD2/3 terminating TGFbeta signaling (potentially associated with depression).
Formal Description Interaction-ID: 32592	gene/protein PPM1A decreases_activity of process transforming growth factor beta receptor signaling pathway

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