General Information:

Id: 3,388 (click here to show other Interactions for entry)
Diseases: Cardiovascular disease
Carnitine deficiency, systemic primary - [OMIM]
Diabetes mellitus, type II - [OMIM]
Insulin resistance
Status epilepticus
Mammalia
review
Reference: Ringseis R et al.(2012) Role of carnitine in the regulation of glucose homeostasis and insulin sensitivity: evidence from in vivo and in vitro studies with carnitine supplementation and carnitine deficiency Eur J Nutr 1: 1-18 [PMID: 22134503]

Interaction Information:

Comment It has been postulated that the reduced transcript levels of the respective genes is due to disruption of peroxisome proliferator-activated receptor alpha (PPARalpha) function in response to high-fat diet administration, because PPARalpha has been identified as a critical transcriptional regulator of BBD, TMABA-DH, and OCTN2 in mice, rats, and pigs.
Formal Description
Interaction-ID: 31823

gene/protein

PPARA

increases_expression of

gene/protein

ALDH9A1

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