General Information:

Id: 3,352
Diseases: Alzheimer disease - [OMIM]
Mammalia
article
Reference: Barrett PJ et al.(2012) The amyloid precursor protein has a flexible transmembrane domain and binds cholesterol Science 336: 1168-1171 [PMID: 22654059]

Interaction Information:

Comment APP has a flexible transmembrane domain (C99) and binds cholesterol.
Formal Description
Interaction-ID: 30774

gene/protein

APP

interacts (colocalizes) with

drug/chemical compound

Cholesterol

via the flexible transmembrane domain C99
Drugbank entries Show/Hide entries for APP or Cholesterol