General Information:

Id: 3,346 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Obesity - [OMIM]
Mus musculus
male
diet-induced obesity (DIO) C57BL/6 mouse
article
Reference: Veniant MM et al.(2009) Time of the day for 11beta-HSD1 inhibition plays a role in improving glucose homeostasis in DIO mice Diabetes Obes Metab 11: 109-117 [PMID: 18479468]

Interaction Information:

Comment Corticosterone circadian rhythm was similar between lean and DIO C57BL/6 mice, and 11beta-HSD1 enzyme activity undergoes minimal variations throughout the day.
Formal Description
Interaction-ID: 30740

affects_activity of

gene/protein

HSD11B1

Drugbank entries Show/Hide entries for HSD11B1