General Information:

Id: 3,340 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Obesity - [OMIM]
Homo sapiens
male
article
Reference: Andrews RC et al.(2003) Effects of the 11 beta-hydroxysteroid dehydrogenase inhibitor carbenoxolone on insulin sensitivity in men with type 2 diabetes J. Clin. Endocrinol. Metab. 88: 285-291 [PMID: 12519867]

Interaction Information:

Comment Carbenoxolone did not affect the rate of glucose disposal or the suppression of free fatty acids during hyperinsulinemia. However, carbenoxolone reduced the glucose production rate during hyperglucagonemia in diabetic patients. This was attributable to reduced glycogenolysis rather than altered gluconeogenesis.
Formal Description
Interaction-ID: 30698

drug/chemical compound

Carbenoxolone

NOT affects_activity of

process

gluconeogenesis

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