General Information:

Id: 3,318 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Obesity - [OMIM]
Homo sapiens
Pima Indians
Reference: Nair S et al.(2004) 11beta-Hydroxysteroid dehydrogenase Type 1: genetic polymorphisms are associated with Type 2 diabetes in Pima Indians independently of obesity and expression in adipocyte and muscle Diabetologia 47: 1088-1095 [PMID: 15156315]

Interaction Information:

Comment Among subjects with normal glucose tolerance, SNP1 (rs846910) and SNP5 rs12086634) were associated with insulin-mediated glucose uptake rates, and SNP1 was further associated with fasting, 30-min, and 2-h plasma insulin concentrations.
Formal Description
Interaction-ID: 30487

affects_activity of


glucose import

in Pima Indians, the risk allele is G